内蒙古大学揭开母体肝脏在孕育与哺乳中的独特代谢秘密|久久99精品国产麻豆婷婷

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  中新网呼和浩特8月29日电 (记者 张玮)29日,内蒙古大学召开新闻发布会,发布该校首次以第一单位在CNS(即《Cell》《Nature》《Science》)正刊上发表的重大研究成果:揭示了母体肝脏在妊娠期与哺乳期会发生独特而有规律的代谢变化。

  内蒙古大学生物医学研究院“骏马计划”研究员杨李介绍,该研究从实验室到草原进行了普遍性论证。结果显示,不论是小鼠还是绵羊,尽管它们在基因调控细节上存在差异,但在妊娠期和哺乳期,肝脏的代谢适应模式高度一致。

  “这说明这一机制在哺乳动物中具有普遍性。”杨李进一步阐释,“母体肝脏在妊娠期和哺乳期的代谢变化,就像一台精密的引擎,一方面要保障胎儿的正常发育,另一方面还要支撑乳汁的分泌。这项研究不仅揭示了其中的关键调控因子,也为改善母婴健康、推动乳品产业升级提供了新的可能。”

图为新闻发布会现场,“骏马计划”研究员杨李介绍研究成果。 中新网记者 张玮 摄

  内蒙古大学学术副校长、生命科学学院院长胡薇表示,本研究将肝脏置于生殖系统的整体研究框架中,为探索器官的适应性与可塑性提供了新的模型;同时,研究提示孕期代谢失衡、胎儿发育受限或产后乳汁不足,可能与肝脏调节不充分有关,为相关疾病的预防和治疗提供了新方向。

  “除此之外,对畜牧学而言,这项研究推动了行业从传统经验育种迈向分子和代谢层面的精准调控,奠定了‘分子畜牧学’的科学基础,标志着草原畜牧业进入精准化发展的新时代;在乳品与营养领域,通过调控关键代谢因子,有望改善乳汁的营养结构,提升乳品的健康价值,同时有助于降低牧业生产成本。”胡薇说。(完)

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